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A meta analysis of seven observational studies comparing dab
2019-06-17
A meta-analysis of seven observational studies, comparing dabigatran with warfarin, indicated that the ability of dabigatran to prevent ischemic stroke and bleeding outcomes is comparable to that of warfarin, which is consistent with the data obtained from the RE-LY trial [9]. These findings do not
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It must be noted that
2019-06-15
It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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br Drug resistant tuberculosis threatens
2019-06-15
Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat
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br Introduction Percutaneous transcatheter device closure of
2019-06-15
Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective
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Lymphocytic infiltrates in thyroid cancer may suggest a back
2019-06-15
Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibo
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br Clinical material br Discussion TLI
2019-06-15
Clinical material Discussion TLI is regarded as a well-tolerated, simple procedure with few acute or late clinical sequelae reported. However, pulmonary irradiation as a therapeutic modality for metastatic bone sarcomas is, although introduced 30 years ago, insufficiently evaluated to clearly
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For the pocket a cm incision was made
2019-06-15
For the pocket, a 6cm incision was made along the predefined Langer’s lines. Subcutaneous dissection was carried out using an electrosurgical cutting and coagulation device, parallel to the incision, down to the fascia overlying the latissimus dorsi muscle (shining transparent membrane). Intermuscu
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The review Bile acid receptor
2019-06-15
The review “Bile purinergic receptors receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic
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Un segundo aspecto que deber a ser considerado para entender
2019-06-15
Un segundo aspecto que debería ser considerado para entender cabalmente por qué estas parentelas nobiliarias indígenas de Xolloco Acatla mostrarían una notable reluctancia GSK2606414 relacionarse con los poderes de San Pablo, y, por el contrario, habrían exhibido una interesada vinculación con los d
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ICG which simply and non invasively measures
2019-06-14
ICG, which simply and non-invasively measures changes in thoracic impedance generated by fluctuating blood volumes during the cardiac cycle, allows for the calculation of stroke volume, CO, and other derived parameters[17]. In recent years, the accuracy of ICG has been greatly improved by the advent
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br Discussion br Conclusions br
2019-06-14
Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia
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Eastern European countries have undergone
2019-06-14
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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OS is Executive Director of the INDEPTH Network PB is
2019-06-14
OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun
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EPZ015666 Interim measures however are not nearly enough
2019-06-14
Interim measures, however, are not nearly enough. A massive expansion of the blood donor pool is needed, but scaling up blood donation in the low-resource world is no easy task. WHO has long advocated a set of interventions to fortify a nation\'s blood supply, but countries will have difficulty solv
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br Maternal and Child Nutrition Series noted the emergence o
2019-06-14
Maternal and Child Nutrition Series noted the emergence of overweight and obesity in low-income and middle-income countries while also documenting the unfinished agenda in undernutrition, sometimes in the same countries and populations. Furthermore, the Series reported analyses of data from Brazil
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