• The pathophysiology underlying ONJ is unclear Decreased bone

  2019-05-15

  

  The pathophysiology underlying ONJ is unclear. Decreased bone remodeling induced by bisphosphonates or inhibition of osteoclast function, which interferes with healing of the microfractures and trauma occurring after dental extraction, have been hypothesized as potential mechanisms for ONJ, but thes

• Preclinical studies have shown that adipocytes and

  2019-05-15

  

  Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer Deferoxamine [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an increase in tumor v

• Este escenario de transformaci n del conflicto en

  2019-05-14

  

  Este escenario de transformación del conflicto en Colombia implica que después de firmado el acuerdo se trabaje, primero, en el triángulo del conflicto que logre la superación de la violencia directa, estructural y cultural en Colombia y, segundo, sobre el triángulo del conflicto que implica las 3R

• Methods We extracted data from the WHO Health

  2019-05-14

  

  Methods We extracted data from the WHO Health Expenditure Observatory and the Institute for Health Metrics and Evaluation\'s Financing Global Health 2015 report. We then adjusted these data by converting to a common, inflation-adjusted currency, and completed the series using multiple imputation. We

• In terms of outcome based assessments we

  2019-05-14

  

  In terms of outcome-based assessments, we analyzed the primary outcomes in both the 7-day and in-hospital mortality, to evaluate further whether the cause of death would be related to acute illness or chronic comorbidities, and furthermore to ensure care quality in both units. Illness severity and t

• In this issue of the Shoja et al characterize

  2019-05-14

  

  In this issue of the , Shoja et al characterize the antimicrobial susceptibility pattern, resistance mechanisms, and typing of carbapenem-resistant (CRAB) isolates obtained from burn patients from a single center in Iran. They found that the rate of CRAB was high (92.5%) among burn patients. The mo

• br Methods br Results br Discussion For the first

  2019-05-14

  

  Methods Results Discussion For the first time, we report the characteristics of meridian acupoint temperatures in healthy medical college students, from which we can construct a meridian acupoint temperature map. The map vividly shows that the acupoint temperature is consistent within a nar

• br Conclusions Based on our

  2019-05-14

  

  Conclusions Based on our findings using a chronic animal model in vivo that repeated VF and defibrillation, not shocks, are associated with striking CaMKII activation, together with accumulating evidence that CaMKII is crucially involved in cellular processes for HF, it is conceivable that CaMKII

• The electrophysiological mechanisms underlying high frequenc

  2019-05-14

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• The aim of this study

  2019-05-14

  

  The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o

• br Conclusions br Acknowledgements This work was supported b

  2019-05-14

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• br Conclusions br Conflict of

  2019-05-14

  

  Conclusions Conflict of interest Introduction Arrhythmogenic right ventricular cardiomyopathy (ARVC), previously called arrhythmogenic right ventricular dysplasia (ARVD), is an inherited disease characterized by right ventricular degeneration and ventricular arrhythmias. ARVC is one of the

• The mean follow up period was months ICD

  2019-05-14

  

  The mean follow-up period was 12 months. ICD discharges and ventricular tachycardia (VT) events were recorded by reviewing Holter, exercise ECG tracings, ICD interrogation reports, and clinic visit notes. Sustained VT was considered as VT with a rate of >100 beats per minute and duration of >30s or

• El libro de William Crawford publicado

  2019-05-14

  

  El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl

• br Clinical characteristics Brugada syndrome

  2019-05-13

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

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