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Despite our best efforts the cause of SCD in young
2019-05-06
Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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Splicing machinery dysfunctions have been associated to CLL
2019-05-06
Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu
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Los muy adeptos Fouchet y Joffroy publican
2019-05-06
Los muy adeptos Fouchet y Joffroy publican sus artículos al calor de la impactante edición francesa de Gallimard, segunda en aparecer (Aub, 1961). Que Aub lograse colocar su obra en el catálogo del sello más importante de Francia se debe, más que al regular contacto con su lugar de nacimiento, AGI-
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Babies and children feature heavily
2019-05-06
Babies and children feature heavily in this August issue of , as well they should at a time when unfinished agendas are top of the agenda. In its 2014 report on the , released on July 7, the UN described the under-5 mortality goal as “slipping away from achievement by 2015”. The research and opinion
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In conclusion describing a single case
2019-05-05
In conclusion, describing a single case observation of a PV-patient we have for the first time delivered the “proof of concept” that combination therapy with Rux and “low-dose” IFN is safe, tolerable and highly efficacious in PV, as evidenced by a rapid reduction in the JAK2V617F-allele burden in co
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br OPG RANK and RANKL contribute
2019-05-05
OPG, RANK and RANKL contribute to the vicious cycle established between tumour ci-1033 and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argume
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Even with the limitations in the available data on
2019-05-05
Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of
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O Comit de Reda o de Araucaria de Chile
2019-05-05
O Comitê de Redação de Araucaria de Chile, que o integrou permanentemente até sua última publicação em 1990, foi composto pelos seguintes intelectuais chilenos: Luis Bocaz, professor, crítico e ensaísta; Osvaldo Fernández, professor de filosofia; e o jornalista Luis Alberto Mansilla. O economista Al
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Brugada syndrome BS is a hereditary arrhythmogenic disease c
2019-05-04
Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada f
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br Case A year old man was
2019-05-04
Case A 45-year-old man was referred for the management of sudden-onset tachycardia. He had experienced 3 episodes of palpitation attacks, lasting for a couple of hours each, during the last 6 months. A regular, wide QRS complex tachycardia (WCT) at 150beats/min with a prominent retrograde P wave
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The management of PEComa follows the same treatment
2019-05-04
The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav
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br D microCT data Bone volume
2019-05-04
3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular apigenin (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published in the li
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br Introduction Atrial fibrillation AF is the most
2019-05-04
Introduction Atrial fibrillation (AF) is the most clinically prevalent tachyarrhythmia [1,2]. AF is a potential risk factor for stroke, and AF-associated strokes are often severe, resulting in disability or death [3–6]. Anticoagulant therapy with the vitamin K antagonist warfarin reduces the risk
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Contrario a lo que concluye Guajardo en torno
2019-05-04
Contrario CM-272 lo que concluye Guajardo, en torno a que la privatización dejó de lado el tema central de la reforma del Estado y de las nuevas capacidades públicas, de ahí que los efectos de décadas de reformas económicas sean todavía confusos e inconsistentes, el fenómeno globalizador sí implicó
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HIV counselling and testing is the
2019-05-04
HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase
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