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In summary this is the first
2021-05-22
In summary, this is the first report describing the enzymatic characteristics, binding activity and localization of T. solium enolase. Here we demonstrate that Tseno gene possesses classical features of enolase family with highly conserved active sites, Mg2+ binding and plasminogen-binding motifs. T
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Another critical finding in this study is that the level
2021-05-22
Another critical finding in this study is that the level of αSyn oligomers in the SN of σ1R−/− mice was progressively increased with age, whereas the levels of αSyn monomers and αSyn messenger RNA (data not shown) were not altered compared to WT mice. A number of studies reported that soluble αSyn m
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Bcl functions as a transcription repressor via
2021-05-22
Bcl6 functions as a transcription repressor via its N-terminal BTB domain and middle “second repression,” or “RD2” domain (Chang et al., 1996, Seyfert et al., 1996). A loss of function of the BCL6 BTB domain markedly impairs survival and proliferation of mature GC Madecassic acid in a B cell intrins
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The fact that the mean tumor size
2021-05-22
The fact that the mean tumor size of the E1202-654 + α-GalCer group was much smaller than that of the α-GalCer inoculated group in both protocols indicates that immunization with E1202-654 plus α-GalCer, which induces a strong CD8+ T cell E1 antigen-specific immune response, is involved in the elimi
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In most cases patients will not present immediately after
2021-05-22
In most cases, patients will not present immediately after SM exposure because SM-induced clinical symptoms typically occur after a latency period of several hours [8], [9], [10]. When they do present, the detection of free, unbound alkylating agent is highly unlikely. For this reason, available rap
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br Materials and methods br Results The BUN
2021-05-22
Materials and methods Results The BUN and creatinine levels in the saline-treated CRF group were found to be significantly higher than those in the sham-operated control rats treated with either montelukast or saline (pBTL-104 receptor tissues, were found to be significantly higher in the sal
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In the pleural exudates which reflect the in
2021-05-22
In the pleural exudates, which reflect the in vivo conditions, the concentrations of CysLTs and PGE2 were quite similar. However, when cancer Barasertib were cultured for 24 h, both analyses of cell culture medium and cell incubations with Ca2+ ionophore showed low levels of CysLTs. In contrast, the
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br Materials and methods br Results and discussion br Conclu
2021-05-21
Materials and methods Results and discussion Conclusions In the present study, we have shown the important role of miR-204-5p in C2C12 myoblast differentiation. Overexpression of miR-204-5p inhibited myogenic differentiation and decreased the formation of slow-twitch myofibers, whereas miR-
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br Lymphoplasmacytic lymphoma Waldenstrom macroglobulinemia
2021-05-21
Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia Lymphoplasmacytic lymphoma (LPL) and its subgroup Waldenstrom macroglobulinemia (WM) are rare and indolent lymphomas that arise from fully differentiated B cells. The only family of GPCRs that has been well studied in LPL/WM is the chemokin
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Some mechanistic experiments performed in the early s
2021-05-21
Some mechanistic experiments performed in the early 2000s by Ongusaha et al. [78], suggest that DDR1 induction protects Free Fatty Acid Quantification Colorimetric/Fluorometric Kit receptor from apoptosis in a p53-dependent manner, and that impairment of DDR1 expression or function leads to a pronou
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The changes in the chemokine receptors
2021-05-21
The changes in the chemokine receptors CCR-5 and CXCR-4 in women and men with PTSD are completely different. In the group of women with PTSD alone the level of this Apicidin increased six times, whereas, in women with APD and PTSD, the level of the receptor CCR-5 was eight times higher than in the c
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The identification of a functional leucine rich NES
2021-05-21
The identification of a functional leucine-rich NES mediating 8E7 nuclear export led us to analyze the interaction between 8E7 and CRM1 nuclear export receptor. HeLa cell lysates containing EGFP-8E7, EGFP–8cE7, EGFP-16E7–NES (as a positive control), or EGFP (as a negative control) were incubated wit
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Instead of introducing extra hardware or hardware modificati
2021-05-20
Instead of introducing extra hardware or hardware modification, software-based CFC techniques just insert extra checking instructions into the source code of the target program at compile time so as to have the target program do checking jobs itself. Preeminent software-based CFC techniques proposed
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br Next let s recall some definitions and notations
2021-05-20
Next, let's recall some definitions and notations from [14] which are necessary to obtain the proof of Theorem 1. Let denote the CMV matrix whose Verblunsky coefficients replaced by , that is The corresponding extended CMV matrix is Recall the definition of in the proof of Theorem 2, replace by
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Octopamine HCl australia br Materials and methods br Results
2021-05-20
Materials and methods Results Discussion Neointimal VSMC accumulation contributes considerably to vessel occlusion observed in both autologous vein graft degeneration [1], [2] and in-stent restenosis [26], [27]. In this study, the potential for retarding VSMC proliferation and hence amelior
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