• Concerning firmness postharvest calcium dips for

  2019-07-02

  

  Concerning firmness, postharvest calcium dips for whole fruit have been demonstrated to preserve firmness, cell wall structure (Glenn and Poovaiah, 1990), nutritional quality (Goldberg, 1984) and fruit flavour (Ortiz et al., 2009). Similarly, combinations of calcium treatment (0.5–4%) with packaging

• axl inhibitor We found all cases to show

  2019-07-02

  

  We found all cases to show at least some IGF-1R expression by immunohistochemistry. This is consistent with its ubiquity at the mRNA or protein level in ES/PNET cell lines or clinical samples as shown by others.12, 14 Evidence that IGF-1R expression is required for EWS-FLI1 transformation of mouse f

• br Results br Discussion Adaptive drug resistance is

  2019-07-02

  

  Results Discussion Adaptive drug resistance is a major challenge to the clinical success of cancer therapies. Incomplete inhibition of oncogenic signaling allows survival of “drug-tolerant” tumor cells, which persist in that state for variable periods before acquiring additional genetic mutati

• In the present study we investigated the

  2019-07-02

  

  In the present study, we investigated the role of EP1R after ICH and its mechanism of action. We hypothesized that EP1R activation aggravates ICH injury but that its blockade reduces injury through the Src kinases and the MMP-9 signaling pathway. To test this hypothesis, we examined the effects of s

• br Materials and methods br Results br Discussion

  2019-07-02

  

  Materials and methods Results Discussion Plant U-box E3 Ub ligases regulate diverse plant-specific cellular processes [1], [2], [3], [4]. However, structural and functional relationships between U-box E3s and their E2 partners are largely unknown in higher plants [24], [25]. In this study,

• br Introduction Concern has been

  2019-07-02

  

  Introduction Concern has been raised over free estrogens (estrone [E1], 17ß-estradiol [E2] and 17α-ethynylestradiol [EE2] particularly) in the past decade due to their endocrine disrupting effects on environmental biota [1], [2]. Estrogens are excreted by vertebrates primarily as sulfate or glucu

• Almost of drugs in the

  2019-07-01

  

  Almost 75% of drugs in the market undergo deactivation though oxidation, reduction or hydrolysis by cytochrome P450 (CYP) enzymes, and then, either directly or by facilitated excretion from the body (Guengerich, 2008). The CYP3A subfamily is of particular interest because of its broad substrate spec

• Berner et al used a meta analysis

  2019-07-01

  

  Berner et al used a meta-analysis to show that sildenafil resulted in an effect of 9.65-point improvement. Tadalafil could be pooled into an effect of 8.52-point improvement, and vardenafil showed an effect of 7.50-point improvement. In our present studies, 200 mg udenafil resulted in an effect of 8

• Countdown to concluded its tasks after the launch of

  2019-07-01

  

  Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he

• In our survey the mean DEFS DMFS

  2019-07-01

  

  In our survey, the mean DEFS/DMFS index was higher for the  6-years-old group (17.18). During early development, younger children often have difficulty carrying out proper oral care due to their physical limitations. After 6 years of age, the exfoliation of primary teeth and the eruption of permanen

• br Methods br Results br Discussion ICC represents an

  2019-07-01

  

  Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi

• There was no significant correlation between the tHcy level

  2019-07-01

  

  There was no significant correlation between the tHcy level and RBC folate level; therefore, we used two-way ANOVA to analyze the relative contributions of serum folate, the C677T genotype, and vitamin B12 to variations in tHcy concentrations. Intervention studies in humans taking folate and/or vita

• Long QT syndrome LQTS a rare inheritable arrhythmia first de

  2019-07-01

  

  Long QT syndrome (LQTS), a rare inheritable arrhythmia first described by Romano and Ward et al. in the 1960s, is characterized by the prolongation of the QT interval on surface ECGs and an increased risk of potentially fatal ventricular arrhythmias, especially torsade de pointes . In 1995, after ye

• Conflict of interest br Introduction Nifekalant hydrochlorid

  2019-07-01

  

  Conflict of interest Introduction Nifekalant hydrochloride was first approved by the Japanese Ministry of Health, Labour and Welfare in 1999 and is now used as a first-line antiarrhythmic drug for refractory ventricular tachyarrhythmias in the country [1]. Nifekalant is a class III antiarrhythmi

• VV optimization From the foregoing discussion

  2019-07-01

  

  VV optimization From the foregoing discussion, it is clear that AV delay programming to ensure ventricular preexcitation with optimal LV diastolic filling and systolic function is complex, and the optimal method that translates into improved patient outcomes is uncertain. These issues are even more

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